Anima

Anima: Beyond Fantasy is an RPG that was originally published in Spanish. It has been translated into English and released in the US by Fantasy Flight Games. Major influences for Anima are traditional RPGs like D&D, console RPGs like Final Fantasy, and various anime and manga series. From the official website: "Anima is a narrative role-playing game developed by Anima Project Studios, conceived as a combination of Japanese and western systems of play, which offers innovative rules and a background that incorporates the most striking elements of both styles."

Anima: Beyond Fantasy has a couple spin-off products. First is a non-collectible card game, "Anima: Shadow of Omega," and the other is a tactical miniatures game, "Anima: Tactics." See the Anima Card Game and Anima Tactics tags for more info on these products.

Links:
Anima Official Website
Anima: Beyond Fantasy on Wikipedia
Anima Official English Forums